STEP 1: GROSS INSPECTION
The ocular assessment begins with careful observation of the patient from a distance without touching the patient (as this may cause distortion of the palpebral fissure). While observing, ask yourself:
STEP 2: ASSESSING VISION
Vision is most commonly tested by evaluating the menace response. This involves making a sudden threatening gesture, which is supposed to elicit a blink response. It is important to note that the menace response involves cerebral cortical integration and interpretation and therefore is not a reflex. The menace response should be evaluated in one eye while the other eye is being covered. Be careful not to touch the eyelashes/hair of the patient or to cause wind movement, as this may lead to a "false positive" response; consider making the menace gesture behind a glass partition.
STEP 3: PUPILS
Use a dim light, and stand at a distance so you can visualize both pupils simultaneously, using the tapetal reflection
Next, use a bright light to evaluate the Pupillary Light Reflex (PLR). Unlike the menace response, the PLR is a subcortical reflex. Therefore, it does NOT test vision, and a normal PLR may be found in a cortically blind animal..
If one of the pupils does not react to light, or if it can’t be visualized (e.g., in cases of hyphema), the consensual PLR should be checked.
STEP 4: EXAMINING THE ANTERIOR STRUCTURES OF THE EYE
The rest of the examination is continued in the dark, using magnification and a focal light source, as the anterior structures of the eye are examined in an anatomical order.
4A: Eyelids & Eyelashes
Evaluate the size of the palpebral fissure, looking for a narrowed or enlarged fissure. Carefully examine the skin, looking for discharge and for signs of dermatological disorders, such as dermatitis, alopecia, scaling, swelling, crusting, ulceration, etc. Pay particular attention to the eyelid margin. In a normal animal, you should see the entire margin in close contact with the globe. Lack of contact may be due to ectropion (drooping lid). On the other hand, if you cannot see the margin, or parts of it, the lid may be everted (entropion). Eyelash abnormalities may be better visualized if the lid is slightly retracted. Dark lashes can then be highlighted against the background of the white conjunctiva.
4B: Third Eyelid & Conjunctiva
At rest, the 3rd eyelid should be mostly retracted and hardly visible. Examine the conjunctiva lining the inner aspect of the eyelids and globe for change in color, congestion, edema, prominent vessels, masses, thickening, discharge, moistness or subconjunctival hemorrhage.
4C: Cornea
The normal cornea should be smooth and transparent. Any deviation from these characteristics represents pathological changes. Look for loss of transparency due to edema, pigmentation, vascularization, cellular infiltration, lipid or mineral deposition, or fibrosis. Look for surface irregularities which may be due to ulceration, perforation and iris prolapse, granulation tissue, or keratoconus.
4D: Anterior Chamber
Assess the depth of the anterior chamber (best visualized from the side), as it may be increased or decreased in various intraocular diseases. In normal animals, the aqueous filling the anterior chamber should be clear. Look for any opacities or masses such as blood, fibrin, hypopyon, aqueous flare, luxated lens, persistent pupillary membranes, iris cysts, or vitreous strands.
4E: Iris & Pupil
Look for alterations in pupil shape, which may be due to adhesions, or iris atrophy, hypoplasia or coloboma. Changes in the color of the pupil may indicate cataract, hemorrhage, or retinal detachment. The size of the pupil may be altered in uveitis, glaucoma and various diseases of the retina or the nervous system.
Examine the surface of the iris for any masses or changes in color. These may be due to inflammation, hemorrhage, or neoplasia. Fluttering of the iris may indicate lens luxation.
4F: Lens
The lens may be examined with direct visualization or by retroillumination using tapetal reflection. The two main pathologies are luxation or opacities, which would indicate cataract
STEP 5: OPHTHALMOSCOPY
Ophthalmoscopy should be conducted in a dark room, following pupil dilation. Carefully inspect the entire fundus, evaluating changes in the tapetum, non-tapetum, blood vessels, and optic disc.
Learning Objectives:-
Areas Covered in the Session:-
Why Should You Attend?
Many veterinarians are apprehensive about performing an ophthalmic examination of their patients. However, ophthalmic examination should not be complicated or expensive! All that’s required is a good light source, a few accessories and drugs, and an understanding of the anatomy of the eye. Following this talk, you will never be scared of doing an ophthalmic examination.
Who will Benefit?
General practitioners; veterinary technicians and nurses.
Ron Ofri was a member of the charter class of the Koret School of Veterinary Medicine, Hebrew University of Jerusalem, Israel. Upon his graduation, he traveled to the University of Florida, where he spent the next 4 years undergoing clinical training in veterinary ophthalmology and obtaining his Ph.D. During this time, Ron developed an interest in the physiology of vision, focusing on retinal electrophysiology and animal models of retinal diseases. Upon his graduation, Ron returned to Israel and joined the faculty of his alma mater, where he is currently a Professor in Veterinary Ophthalmology and winner of numerous Teacher of the Year awards. At the Hebrew University of Jerusalem, Ron expanded his research interests to include clinical veterinary ophthalmology (focusing on glaucoma and retinal diseases) and retinal gene therapy. His groundbreaking work on retinal gene therapy on a herd of sheep with naturally occurring day blindness has resulted in the restoration of vision in treated animals for >6 years and has paved the way to FDA approval of Phase I/IIa clinical trials in human patients. Ron is also a very popular international speaker, having been invited to talk in more than 40 countries and 6 continents, lecturing in continuing education seminars, national & international meetings, and world congresses for general practitioners, including BSAVA, SEVC, WSAVA, WVC, WVAC, and NAVC/VMX. He also lectures frequently in advanced training courses for veterinary ophthalmologists, including lectureship at the Basic Science Course of the American College of Veterinary Ophthalmologists (where he has been speaking since 2002) and numerous other forums. And during the COVID pandemic, he has given dozens of online lectures. Ron has published more than 120 peer-reviewed papers and is a contributing author to the Gelatt's classic textbook Veterinary Ophthalmology (3rd, 4th, 5th and 6th editions) as well as co-author of the popular textbook Slatter's Fundamentals of Veterinary Ophthalmology (4th, 5th and 6th editions, below). Ron is a Diplomate of the European College of Veterinary Ophthalmology (ECVO), a former ECVO Executive Board member and Scientific Committee member, and in 2002-2005, he served as President of the European Society of Veterinary Ophthalmology.
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